Incidental empty sella11/23/2023 ![]() Case report: Development of an empty sella in neurosarcoidosis. Empty sella syndrome information page.(n.d.).You can learn more about how we ensure our content is accurate and current by reading our editorial policy. Healthline has strict sourcing guidelines and relies on peer-reviewed studies, academic research institutions, and medical associations. conditions related to the brain or pituitary gland, such as Sheehan syndrome, intracranial hypertension, neurosarcoidosis, or hypophysitis.radiation therapy or surgery in the area of the pituitary gland.Secondary empty sella syndromeĪ number of things can cause secondary empty sella syndrome, including: However, most cases of empty sella syndrome go undiagnosed due to their lack of symptoms, so it’s hard to say whether gender, obesity, age, or blood pressure are true risk factors. Most women with empty sella syndrome tend to be middle-aged, obese, and have high blood pressure. Doctors aren’t sure whether this is a direct cause of empty sella syndrome or simply a risk factor.Īccording to the National Organization for Rare Disorders, empty sella syndrome affects about four times as many women as it does men. Some people are born with a small tear in the diaphragma sellae, which can cause CSF to leak into the sella turcica. It may be related to a birth defect in the diaphragma sellae, a membrane that covers the sella turcica. The exact cause of primary empty sella syndrome isn’t clear. Alexandria Journal of Medicine, 47, 139-147.What are the causes? Primary empty sella syndrome (2011) Review of Empty Sella Syndrome and Its Surgical Management. Journal of Clinical Endocrinology & Metabolism, 90, 5471-5477. Indian Journal of Endocrinology and Metabolism, 16, S321-S323.ĭe Marinis, L., Bonadonna, S., Bianchi, A., Maira, G. (2012) Empty Sella Syndrome-Beyond Being an Incidental Finding. (1995) 43 Cases of Primary Empty Sella Syndrome: A Case Series. Minerva Endocrinologica, 14, 1-18.īragagni, G., Bianconcini, G., Mazzali, F., et al. Clinical, Radiological and Endocrinologic Analysis in 20 Cases. Ann Endocrinol (Paris), 46, 99-105.ĭegli, U.E.C., Teodori, V., Trasforini, G., et al. Analysis of 14 Cases and Review of Literature. Īrlot, S., Lalau, J.D., Galibert, P., et al. (1972) The Symptomatic Empty Sella: Prevention and Correction via the Transsphenoidal Approach. and Rengachery, S., Eds., Neurosurgery, McGraw-Hill, New York, 1367-1373. British Journal of Hospital Medicine, 47, 523-525. (1992) The Empty Sella Syndrome: Much Do about Nothing. She was treated conservatively and regular follow-up was advised.īraatvedt, G.D. ![]() MRI brain revealed presence of Empty Sella. On evaluation, she was detected to have impaired blood sugars, dyslipidemia and vitamin insufficiency. Examination was unrevealing except for the fact that she was obese. In this report, we presented a 41-year-old multiparous patient who presented to us with symptoms of headache and left sided hemi-sensory disturbance. An empty sella may be classified as primary when this occurs in persons who have not received pituitary radiation or pituitary surgery, while an empty sella discovered following such procedures is classified as secondary empty sella. Compression of the pituitary gland may affect function, or traction on the optic chiasm and nerves may cause visual symptoms. However, it can be a manifestation of increased intracranial pressure and can be occasionally severe. Empty sella syndrome is considered as a less common entity and is usually asymptomatic and an incidental finding. Over time, cerebrospinal fluid (CSF) pulsations may enlarge the sella and compress the gland against the floor of the sella. An empty sella occurs due to herniation of the arachnoid through an incompetent diaphragma sellae.
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